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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRIN2D All Species: 34.85
Human Site: S539 Identified Species: 76.67
UniProt: O15399 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15399 NP_000827.2 1336 143752 S539 R A D M A I G S L T I N E E R
Chimpanzee Pan troglodytes Q5IS45 1464 165261 S511 R A V M A V G S L T I N E E R
Rhesus Macaque Macaca mulatta XP_001088140 1484 166333 S512 R A Y M A V G S L T I N E E R
Dog Lupus familis XP_540421 1081 117358 D371 N V T W E G R D F S F S P G G
Cat Felis silvestris
Mouse Mus musculus Q03391 1323 142890 S536 R A D M A I G S L T I N E E R
Rat Rattus norvegicus Q62645 1323 143083 S536 R A D M A I G S L T I N E E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506052 1465 164998 S509 R A V M A V G S L T I N E E R
Chicken Gallus gallus XP_425252 1458 165503 S508 R A V M A V G S L T I N E E R
Frog Xenopus laevis NP_001106367 1451 164575 S503 R A V M A V G S L T I N E E R
Zebra Danio Brachydanio rerio XP_001921158 1916 210798 S560 R A D M A I G S L T I N E E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24418 997 112270 L287 D G V L G L Q L E H A H S D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.2 39.2 48.1 N.A. 96.4 96.3 N.A. 41.2 39.9 40.8 40.9 N.A. 22 N.A. N.A. N.A.
Protein Similarity: 100 54.4 52.8 58.2 N.A. 96.7 96.7 N.A. 54.4 53.7 54.3 49.4 N.A. 36.9 N.A. N.A. N.A.
P-Site Identity: 100 86.6 86.6 0 N.A. 100 100 N.A. 86.6 86.6 86.6 100 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 13.3 N.A. 100 100 N.A. 93.3 93.3 93.3 100 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 82 0 0 82 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 37 0 0 0 0 10 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 0 0 0 10 0 0 0 82 82 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % F
% Gly: 0 10 0 0 10 10 82 0 0 0 0 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 37 0 0 0 0 82 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 10 0 10 0 10 82 0 0 0 0 0 0 % L
% Met: 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 82 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 82 0 0 0 0 0 10 0 0 0 0 0 0 0 82 % R
% Ser: 0 0 0 0 0 0 0 82 0 10 0 10 10 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 82 0 0 0 0 0 % T
% Val: 0 10 46 0 0 46 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _